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Menopause
New Premature Ovarian Insufficiency Clinical Trial

Menopause before the age of 40?

💡Help researchers learn more about a new potential therapy for premature ovarian syndrome (POI).

💡Qualify to take part and you could receive study-related care at no cost, as well as compensation.

Click here or scroll down to learn about this study's inclusion criteria ⬇️

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If you take part in the research study, there will be:

Reimbursement of travel costs

Free study-related medical care

No overnight stays!

All study visits are out-patient only.

🏥 Study Guide

Who can take part in this study?

In order to be eligible to participate in the study, you must meet all of the following:

  • You are aged between 18 and 44
  • You have experienced menopause OR had both ovaries removed before 40 years of age 
  • You have been on a stable dose of oestrogen replacement therapy (ERT) for at least 3 months.
  • Your body mass index is between 18 and 38.


Who is unable to take part in this study?

Unfortunately, if you have a history of a known bone disease or a condition associated with osteoporosis, this study is not the right fit for you.



How long will the study take?

If you agree to take part, and the study is suitable for you, your participation in the study is expected to last up to 12 months. This may include:

  • Screening period (2-4 weeks): 1 visit to the study centre
  • Treatment period (12 months): 4 visits to the study centre for 60-90 minutes at a time.
  • Blood collection and bone density scans at the beginning and end of the trial.

What is the purpose of this study?

This study aims to determine whether testosterone therapy is effective in preventing bone loss and improving sexual function in women with premature ovarian insufficiency (POI) who are taking the standard dose of oestrogen. Join and do your part to help advance breakthroughs in this clinical research.

What is premature ovarian insufficiency?

Almost 4 in every 100 Australian women go through menopause before they reach the age of 40. This loss of ovarian function is called premature ovarian insufficiency (POI).

Women with POI do not produce adequate levels of oestrogen or testosterone needed for good bone health. For this reason, they experience progressive bone loss which increases the risk of osteoporosis and fractures at a young age. Despite adequate estrogen replacement many women with POI also experience sexual dysfunction.

Where is my nearest study site?

Here is a list of all of the sites who are currently recruiting for this study:

  • VIC, Melbourne - The Women’s Health Research Program, Monash University
  • VIC, Melbourne, Clayton - Monash University, Monash Health
  • WA, Perth, Nedlands - The Keogh Institute of Medical Research 

What if I have other questions about the study?

We are here for you! Click or tap this button to send an email to our Patient Experience team: