Brand New Medical Study
Let's try and put an end to neuropathic pain (nerve pain)
💡 Investigating a potential new treatment for lower back pain (lumbar radiculopathy)
💡Reimbursement of costs (for out-of-pocket expenses, such as travel and meals)
📝 Registration Form
🏥 Study Guide
What is lumbar radiculopathy?
A pinched nerve in your lower back, or lumbar radiculopathy, can be painful and debilitating. It may appear out of nowhere or it could be the cause of a traumatic injury. You’re more likely to experience symptoms as you get older. This is because your vertebrae compress with age and the discs in your vertebrae degenerate over time.
The cushioning between your spine lessens as you age and can lead to nerve pain. Bone spurs and other degenerative conditions can occur as you age as well, leading to a pinched nerve.
The pain has been described as a burning, shooting or crawling sensation or like electric shocks, and there are often other sensations, such as numbness or pins and needles that accompany the pain.
Lumbar radiculopathy is often severe, ongoing (chronic) and can be difficult to treat.
Who can take part in this study?
In order to be considered to take part in the study, you’ll need to meet all of the following:
- You are between 18 and 80 years of age
- You have been suffering from a pinched nerve in your lower back, or lower back pain with radiation down one or both legs
- You have experienced painful symptoms such as; weakness, sharp pain, numbness or pins and needles in your lower limbs
- You have tried neuropathic pain treatments for 3 months or more, with no effect on the pain
Who is unable to take part in this study?
Unfortunately, you would not be able to participate in the study if you meet any of the following:
- Anyone who has previously had back surgery or lower back surgery
- Anyone who has participated in another clinical study within the last 30 days
- Any women who are currently pregnant or lactating
- Anyone who is an insulin-dependent diabetic
- Anyone who has had cancer (with the exception of non-melanoma skin cancers) within the last 5 years
- Anyone currently suffering from angina or heart failure
How long will the study take?
If you agree to take part, and the study is suitable for you, your participation in the study could last up to 180 days. This includes:
- 1 screening visit at the study site
- 1 study dosing visit (approx. 8 hours)
- 8 follow-up visits at the same study site
What is the purpose of this study?
Lumbar radiculopathy or nerve pain in general, can be very difficult to treat, with only 40-60% of people achieving partial relief. This research project is investigating a potential new treatment.
The study will evaluate an experimental treatment product called XT-150, which may eventually be used for the treatment of lumbar radiculopathy, as well as other causes of neuropathic pain. The main purpose of this study is to assess the safety, tolerability and efficacy of the experimental treatment.
Where is my nearest study site?
Here is a map of all of the sites who are currently recruiting for this study:
What if I have other questions about the study?
We are here for you! Click or tap this button to send an email to our Patient Experience team: