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Clinical Trial of a COVID-19 Vaccine and Flu Vaccine

New Vaccine Clinical Trial for COVID-19 and Flu

💡 Help researchers by participating in an investigational study to learn more about the safety and immune responses of a COVID-19 vaccine administered together with the annual flu vaccine.

Click here or scroll down to learn about this study's inclusion criteria ⬇️

How did you hear about this study?

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If you take part in the research study you will receive:

Reimbursement of costs

For out-of-pocket expenses, such as travel  and parking.

Advance medical science

Do your part to potentially advance breakthroughs in clinical research.

No overnight stays!

All study visits are out-patient only.

🏥 Study Guide

Who can take part in this study?

In order to be eligible to participate in the study, you must meet all of the following (and some other specific criteria):

  • You are aged 18-64 years old
  • Have received 3 prior doses of the Pfizer-BioNTech COVID-19 vaccine
  • You are generally healthy, or you have a stable chronic disease


Who is unable to take part in this study?

Unfortunately, if you meet any of the following, this study is not the right fit for you:

  • Anyone who has a history of a severe allergic reaction to a vaccine
  • Anyone who has a known or suspected condition that weakens their immune system
  • Anyone who is pregnant or breastfeeding
  • Anyone who has already received the flu vaccine in the past 6 months
  • Anyone who has received any COVID-19 vaccine other than the Pfizer-BioNTech COVID-19 vaccine

How long will the study take?

If you agree to take part, and the study is suitable for you, your participation in the study is expected to be approximately 2 months. This includes blood tests and other study procedures at:

  • 3 visits to the study site (2 vaccination visits, and 1 follow-up visit) about 1 month apart
  • Use of an electronic diary for 7 days after each vaccination visit to record any side effects you might have 

What is the purpose of this study?

We are inviting people to participate in an investigational study that will help researchers learn more about the safety and immune responses of the Pfizer-BioNTech COVID-19 vaccine administered together with the annual flu vaccine. The effects of giving the COVID-19 vaccine and flu vaccine together have not been studied and the administration of these two vaccines at the same time is considered investigational for the purposes of this research study. 

All eligible participants will receive the Pfizer-BioNTech COVID-19 vaccine and the flu vaccine, with some participants receiving both vaccines at the same time and others receiving them about 1 month apart. 

Where is my nearest study site?

Here is a list of all of the sites who are currently recruiting for this study:


  • NSW, Brookvale (Northern Beaches Clinical Research)
  • NSW, Maroubra (Australian Clinical Research Network)
  • NSW, Westmead (Westmead Hospital)
  • VIC, Camberwell (Emeritus Research)
  • VIC, Geelong (Barwon Health)
  • QLD, Albion (Paratus Clinical Research Brisbane)
  • QLD, Milton (Core Research Group)
  • QLD, Tarragindi (AusTrials – Wellers Hill)

New Zealand

  • Auckland, Birkenhead (Southern Clinical Trials Waitemata Ltd)
  • Auckland, Grafton (Optimal Clinical Trials)
  • Auckland, Grafton (New Zealand Clinical Research (Auckland))
  • Auckland, New Lynn (Southern Clinical Trials Totara)
  • Auckland, Papatoetoe (Middlemore Hospital)
  • Bay of Plenty, Papamoa (Lakeland Clinical Trials , Culloden Research)
  • Bay of Plenty, Rotorua (Lakeland Clinical Trials)
  • Canterbury, Christchurch Central City (Southern Clinical Trials Ltd)
  • Canterbury, Christchurch Central City (New Zealand Clinical Research (NZCR CHC))
  • Hawke's Bay, Havelock North (P3 Research, Hawke's Bay)
  • Manawatu-Wanganui, Palmerston North Central (P3 Research, Palmerston North)
  • Nelson, Stoke (Southern Clinical Trials Tasman)
  • Upper Hutt, Ebdentown (Lakeland Clinical Trials Wellington)
  • Waikato, Nawton, (Lakeland Clinical Trials, Waikato)




What is COVID-19?

Coronaviruses are a large family of viruses that cause respiratory infections, ranging from the common cold to more serious diseases. COVID-19 is an infectious disease caused by the SARS-CoV-2 virus. The virus spreads quickly through small liquid particles from an infected person's mouth or nose when they cough, sneeze, speak, or breathe. For this reason it is important to protect yourself and others by maintaining good personal hygiene, wearing a mask, and practising social distancing. 

Of those infected with the virus, most will experience mild to moderate respiratory illness and recover without requiring serious medical intervention. However, some will become seriously ill and require medical attention. Those at greater risk of developing serious illness are older people and those with underlying medical conditions like cardiovascular disease, diabetes, chronic respiratory disease, or cancer. 

Common symptoms include fever, dry cough, tiredness, and loss of taste or smell. Other symptoms that may appear less often are a runny nose or congestion, headache or fatigue, muscle/joint pains, nausea or loss of appetite, and diarrhoea or vomiting. 

(For more information, see https://www.who.int/health-topics/coronavirus#tab=tab_1.)


COVID-19 vs. Flu

COVID-19 and the flu have a number of similarities and differences. Let’s take a look at some key characteristics of each condition and how they compare. 



  • Both are contagious respiratory diseases caused by viruses. 
  • COVID-19 is caused by a coronavirus called SARS-CoV-2, while the flu is caused by influenza A and B viruses.


  • Both include symptoms such as fever, cough, shortness of breath, tiredness, sore throat, runny nose, muscles aches, headache, and nausea or vomiting
  • Symptoms of COVID-19 generally appear 2-14 days after exposure, while flu symptoms appear more rapidly, 1-4 days post-exposure.


  • Both spread between people in close contact (through respiratory droplets/aerosols)
  • COVID-19 appears to be more contagious and spread at a higher rate than the flu.


  • The flu can be treated with antiviral medicines.
  • There are antiviral medicines (oral and intravenous)approved for the treatment of COVID-19, for use in people who are already in the hospital, or for people who may be at risk for developing more severe symptoms.
  • Antiviral medicines are not a substitute for vaccination and do not replace the need for vaccination.


  • The annual flu vaccine is recommended to prevent flu, particularly in adults at risk of becoming seriously ill, such as older adults and those with chronic medical conditions
  • The COVID-19 vaccine is recommended to prevent COVID-19 infection, particularly in people with underlying health conditions and some older people who are at higher risk of serious illness from COVID-19

For more information, see:

What if I have other questions about the study?

We are here for you! Click or tap this button to send an email to our Patient Experience team: